http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109364035-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4168 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4168 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 |
| filingDate | 2018-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109364035-B |
| titleOfInvention | A kind of clonidine hydrochloride sustained-release tablet and preparation method thereof |
| abstract | The invention relates to a clonidine hydrochloride sustained-release tablet and a preparation method thereof, belonging to the field of pharmaceutical preparations. The clonidine hydrochloride sustained-release tablet of the present invention is composed of: 0.1-0.5 parts of active ingredients, 8-18 parts of composite polymer skeleton system, 10-18 parts of disintegrant, 12-18 parts of binder, and 15 parts of diluent. -30 parts, lubricant 0.1-2 parts, the active ingredients are composed of clonidine hydrochloride and scutellarin, and the composite polymer framework system is composed of methyl cellulose and polyvinyl alcohol. In the present invention, the combined application of clonidine hydrochloride and scutellarin is used for the preparation of slow-release tablets for reducing blood pressure for the first time. By optimizing and screening the formula, it is found through the effect test study that the combined application of clonidine hydrochloride and scutellarin can significantly improve blood pressure. A synergistic effect was achieved. |
| priorityDate | 2018-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.