http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109336969-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 |
| filingDate | 2018-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109336969-B |
| titleOfInvention | Antibody purification method |
| abstract | The invention provides a method for purifying an antibody. A method for purifying an antibody comprising a protein a affinity chromatography step; the protein A affinity chromatography method comprises the following steps: after loading and before eluting the target antibody with an eluent, washing the column bed with an intermediate washing buffer; the intermediate washing buffer solution is: a buffer solution with pH value of 5-6 and conductivity of 20-100 mS/cm. The invention improves the removal capacity of HCP and DNA by adding the step of intermediate cleaning in the protein A affinity chromatography process, thereby improving the virus removal capacity of anion exchange chromatography. |
| priorityDate | 2018-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.