http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109336856-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd37b53f7a639daf413b490204ba4613 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-30 |
| filingDate | 2018-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d61e9175ee2a50411e9a1df1e2dd31dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_864a84de006456d0b8ae4a168d42b254 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cabd0bc92b6fecd7e6804e25edbd59b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e87a02fdca5963a18b156169c27be9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d717b249adb112925b4878bf2b1cc86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cb1c4d6ae343917f5241e32c08fc1c2 |
| publicationDate | 2019-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109336856-A |
| titleOfInvention | A kind of preparation method of 6-bromo-D-gluculose |
| abstract | The invention discloses a preparation method of 6-bromo-D-gluculose, and the reaction route is: The preparation steps are: (1) using glucose as a starting material, reacting in a sodium acetate/acetic anhydride system to obtain compound 1; (2) reacting compound 1 with a hydrobromide acetic acid solution in a dichloromethane system to obtain a compound 2; (3) Compound 2 was reacted with zinc powder in acetone/saturated sodium dihydrogen phosphate system to obtain compound 3; (4) Compound 3 was reacted in methanol/sodium methoxide system to obtain D-gluculose, and then in pyridine Compound 4 was prepared by reacting with TsCl and acetic anhydride successively in the /methylene chloride system; (5) Compound 4 was reacted with LiBr in DMSO system to prepare compound 5; (6) Compound 5 was prepared by reacting in sodium methoxide/methanol system Compound 6. The preparation method of 6-bromo-D-gluculose of the present invention has the advantages of simple operation, mild reaction conditions, cheap and easily available raw materials, high yield and low cost, and is suitable for mass industrial production. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114456217-A |
| priorityDate | 2018-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.