http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109331794-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2479-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08K5-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2333-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-28007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-28019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-246 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-268 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-28009 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08K5-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L79-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-30 |
| filingDate | 2018-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109331794-B |
| titleOfInvention | Dopamine and metabolite molecular imprinting magnetic nanosphere thereof, and preparation method and application thereof |
| abstract | The invention discloses a dopamine and metabolite molecular imprinting magnetic nanosphere as well as a preparation method and application thereof. The method comprises the following steps: synthesizing the magnetic nanospheres with the carboxyl functionalization by a hydrothermal method; adding the carboxyl functionalized magnetic nanospheres and two kinds of epinephrine metabolites into a phosphate buffer solution according to a certain proportion to obtain a double-template-carrier compound; stirring the separated mixture, functional monomer hyperbranched polyethyleneimine and cross-linking agent glutaraldehyde in a phosphate buffer solution for polymerization to obtain a polymer; separating the solid polymer by an external magnetic field; and finally, refluxing and eluting the solid polymer, and drying in vacuum to obtain the dopamine and metabolite molecular imprinting magnetic nanospheres thereof. The preparation method is simple and mild in condition, and the prepared molecular imprinting magnetic nanospheres are uniform in particle size, strong in stability and good in water solubility, and can be used for simultaneously and rapidly realizing selective enrichment and detection of dopamine and 3,4-dihydroxy phenylacetic acid in a complex matrix of human body fluid. |
| priorityDate | 2018-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.