http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109330931-B

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-805
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-9789
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-9789
filingDate 2018-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109330931-B
titleOfInvention Centella asiatica extract applied to cosmetics and preparation method thereof
abstract The invention discloses a centella extract applied to cosmetics and a preparation method thereof. The invention comprises the following steps: 1: taking dry whole plant of the centella asiatica, crushing, mixing with an ethanol solution, refluxing, heating, filtering and collecting filtrate; 2: concentrating the filtrate into thick paste, and adding water to obtain herba Centellae concentrated solution; 3: extracting the centella concentrated solution by using petroleum ether, and recovering the petroleum ether under vacuum and reduced pressure to obtain a petroleum ether part sample. 4: extracting the residual concentrated solution with ethyl acetate, and recovering ethyl acetate under reduced pressure to obtain an ethyl acetate part sample. 5: performing silica gel column adsorption on the ethyl acetate part sample, eluting with a mixed solvent of petroleum ether and acetone in a volume ratio of 5:1 and 4:1, eluting with a mixed solvent of petroleum ether and acetone in a volume ratio of 2:1, collecting the eluted solvent of petroleum ether and acetone in a volume ratio of 2:1, evaporating the solvent under reduced pressure, and collecting the target sample. 6: and (3) carrying out vacuum drying on the target sample to obtain the asiatic pennywort herb extract. The invention has good separation effect, recycles the organic solvent and reduces the pressure of environmental pollution.
priorityDate 2018-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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