http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109321610-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9de52bba13e16028dffa8775e3f3f28 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y206-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1096 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
| filingDate | 2018-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6281d35db8088e8126801aae15e4e9bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76d0d8f53cf57b61a7961ba5bfa7725d |
| publicationDate | 2019-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109321610-A |
| titleOfInvention | Efficient Preparation of 2-Amino-1,3-Propanediol by Microbial Fermentation |
| abstract | The invention provides a microbial fermentation method for efficiently preparing 2-amino-1,3-propanediol. Specifically, the present invention designs and constructs an artificial biosynthesis pathway for 2-amino-1,3-propanediol, and successfully constructs a recombinant genetically engineered strain for biosynthesizing 2-amino-1,3-propanediol. The present invention utilizes protein engineering technology to obtain fusion engineering protein with single activity of phosphate dihydroxyacetone aminotransferase for the first time. After systematic optimization of metabolic pathways, an artificial biosynthetic pathway with clear biosynthetic pathway and efficient and stable operation was obtained for the first time, and a recombinant engineering strain and fermentation process for efficient and stable synthesis of 2-amino-1,3-propanediol using a simple carbon source for one-step fermentation were established. The process laid the foundation of catalytic elements, synthetic pathways and strain systems for the efficient preparation of 2-amino-1,3-propanediol by large-scale biological fermentation. |
| priorityDate | 2018-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 624.