http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109321609-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-42 |
| filingDate | 2018-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109321609-B |
| titleOfInvention | Method for preparing R-mandelic acid by using microchannel reaction device |
| abstract | The invention discloses a method for preparing R-mandelic acid by using a microchannel reaction device, which comprises the steps of dissolving mandelate in a first organic solvent to obtain a mixed solution A; dissolving lipase in a phosphate buffer solution to obtain a mixed solution B; simultaneously pumping the mixed solution A and the mixed solution B into a mixer of the microchannel reaction device for mixing, and then entering a reactor of the microchannel reaction device for enzyme-catalyzed ester hydrolysis reaction; after the reaction is finished, collecting effluent liquid of the reactor, separating liquid, taking a lower-layer water phase, adding a second organic solvent into the water phase for extraction, and then using anhydrous Na 2 SO 4 Drying, and finally removing the organic solvent by rotary evaporation to obtain the R-mandelic acid. The method carries out enzyme catalysis mandelic ester hydrolysis by changing the residence time of reaction materials in the microchannel reaction device, can obtain mandelic acid with single isomer, accelerates the reaction rate, improves the optical selectivity of mandelic acid, and has the advantages of simple process, short reaction time and the like. |
| priorityDate | 2018-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.