http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109320557-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0459 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F13-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F13-00 |
| filingDate | 2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109320557-B |
| titleOfInvention | 99mTc(CO)3Nuclear-labeled isonitrile-containing palbociclib derivative and preparation method and application thereof |
| abstract | The invention discloses a 99m Tc(CO) 3 A nuclear-labeled isonitrile-containing palbociclib derivative having the general molecular formula [, [ 2 ] 99m Tc(CO) 3 (CNPBB) 3 ] + In the structural formula: to be provided with 99m Tc(CO) 3 The core is a central core, and the carbon atom of the isonitrile group in the CNPBB ligand molecule is substituted 99m Tc(CO) 3 (H 2 O) 3 ] + After formation of water molecules on the intermediate body 99m Tc(CO) 3 (CNPBB) 3 ] + A complex wherein n is equal to 2 and 3. By synthesis of ligands CN2PBB and CN3PBB, the complex 99m Tc(CO) 3 (CN2PBB) 3 ] + and [ 99m Tc(CO) 3 (CN3PBB) 3 ] + the specific preparation steps of (2) to obtain 99m Tc(CO) 3 (CN3PBB) 3 ] + And (3) a complex. The complex has high radiochemical purity and good stability, and is applied to the field of nuclear medicine as a tumor imaging agent. |
| priorityDate | 2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.