http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109316485-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0071 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-80 |
filingDate | 2018-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109316485-B |
titleOfInvention | Anti-tumor application of covalent organic framework material |
abstract | The invention provides application of a covalent organic framework material in preparation of one or more of tumor treatment drugs, photodynamic therapy drugs and photothermal therapy drugs; the covalent organic framework material has a structure shown in a formula (I). The covalent organic framework material with the structure of formula (I) is used in medicaments for treating tumors, medicaments for photodynamic therapy and medicaments for photothermal therapy, can release heat after light excitation, thereby realizing the photothermal therapy of tumors, and can realize the synergistic therapy of photodynamic and photothermal under single wavelength, thereby realizing powerful killing of cells. In addition, the invention also finds that the covalent organic framework material has an EPR effect, improves the enrichment of the nanosheet in an in vivo experiment, has the photoacoustic imaging capability, and can determine the optimal enrichment time of the covalent organic framework material, thereby realizing tumor treatment under the guidance of imaging. |
priorityDate | 2018-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.