http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109316447-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
filingDate | 2018-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109316447-B |
titleOfInvention | Functionalized liposome and preparation method and application thereof |
abstract | The invention mainly relates to a functionalized liposome and a preparation method and application thereof. The polypeptide molecule without biological activity forms a phospholipid-polypeptide-phospholipid conjugate with phospholipid through coupling reaction and displacement reaction, and the liposome is synthesized through the prepared conjugate and phospholipid/cholesterol/phospholipid-PEG, so that the polypeptide modified liposome is obtained. The polypeptide on the surface of the liposome is stably present on the surface of the liposome in an arc shape. Under proper conformation regulation, inactive polypeptide is endowed with biological activity, so that the targeted liposome-based artificial antibody is constructed. |
priorityDate | 2018-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.