http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109313135-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D285-14 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
filingDate | 2017-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109313135-B |
titleOfInvention | Aggregation-induced luminophores for imaging cancer cells |
abstract | The present application relates to luminophores exhibiting aggregation-induced luminescence, wherein Tl, T2 and T3 comprise one or more polyynes as conjugated bridges. The present application also relates to an AIEgen comprising: a hydrophilic pyridyl group as a strong electron withdrawing group; a piperazine group and an α-cyanostilbene group as an electron donating group; wherein the AIEgen exhibits aggregation Induces luminescence. The present application also relates to a method of synthesizing AIEgen, and further relates to a method of labeling, the method comprising: incubating an object having cells with a conjugate formed by coupling AIEgen to an antibody; and selecting by light-up imaging Cells of interest are selectively labeled by selective staining of the cells of interest by AIEgen's fluorescence emission based on antibody degradation following cellular internalization of the conjugate by endocytosis. |
priorityDate | 2016-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 104.