| abstract |
The present invention provides bispecific antibody constructs of specific Fc mode, characterized by comprising a first domain that binds to PSMA, a second domain that binds to the extracellular epitope of the human and cynomolgus CD3ε chain; and a third domain , which is the specific Fc pattern. Furthermore, the present invention provides polynucleotides encoding the antibody constructs, vectors comprising such polynucleotides, host cells expressing the constructs, and pharmaceutical compositions comprising the same. |