http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109311907-B

Outgoing Links

Predicate Object
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04
filingDate 2017-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109311907-B
titleOfInvention Preparation method of high-purity prasugrel
abstract The field of the present invention relates to a new high-purity 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4 of formula (I) suitable for industrial scale preparation ,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate, the preparation method of prasugrel. Especially in large scale production, one of the main reasons for impurity build-up is the use of ether solvents, therefore ethers are excluded in every step of the process. Avoiding ethers in different steps of our method leads to new conditions for the production of intermediates. Conditions are determined so that each step from the beginning helps to minimize the impurity content of the final product.
priorityDate 2016-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

Predicate Subject
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012018791-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012001486-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009062044-A3
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID406903349
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID175
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6918456
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419480215

Total number of triples: 17.