abstract |
Provided herein are methods of generating Natural Killer (NK) cells and/or ILC3 cells using a three-stage expansion and differentiation method using a medium comprising stem cell mobilization factors. Also provided herein are methods of inhibiting tumor cell proliferation using NK cells and/or ILC3 cells and populations of NK cells and/or ILC3 cells generated by the three-stage methods described herein, and methods of treating individuals with cancer or viral infections , which comprises administering NK cells and/or ILC3 cells and populations of NK cells and/or ILC3 cells generated by the three-stage method described herein to an individual suffering from cancer or a viral infection. |