http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109295218-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
filingDate | 2018-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109295218-B |
titleOfInvention | Circular RNA marker hsa _ circ _0001788 and application thereof |
abstract | The invention establishes a circRNA expression profile of a craniosynostosis patient, provides a serum circRNA marker hsa _ circ _0001788 of the craniosynostosis patient, discloses the diagnostic value of the serum hsa _ circ _0001788 on craniosynostosis, is used for preparing a diagnosis kit of the craniosynostosis patient, and provides support for the early discovery and treatment of the craniosynostosis patient clinically. The serum circRNA has the advantages of good stability, difficult degradation and the like, has higher auxiliary diagnostic value, and is beneficial to clinical popularization and use. The inventor adopts a circRNA chip for detection to obtain a serum circRNA expression profile of disease specificity and abnormal expression, and verifies the serum circRNA expression profile by using a qRT-PCR method, and the method has a strict design and evaluation system. The invention finds that hsa _ circ _0001788 in serum is used as an important biological detection index for the first time, the detection index is minimally invasive and cheap, can be applied to clinical detection, and has important effects on early diagnosis and differential diagnosis of craniosynostosis clinic. |
priorityDate | 2018-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.