Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
filingDate |
2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23421acdfe7b2a17439fb2e480e6a025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d28a818cc540d53fe94d13f5524e0b46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6298277740ecba24576e35d768e8429 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c66286a6a81f696c0d1585c37bb2933d |
publicationDate |
2019-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-109293632-A |
titleOfInvention |
A non-reactive mitochondrial tracking fluorescent probe containing dodecyl chain and its application |
abstract |
The invention discloses a non-reactive mitochondrial tracking fluorescent probe containing a dodecyl chain and its application in labeling or displaying the distribution of mitochondria in cells and in the observation of mitophagy; the fluorescent probe is The carbazole pyridine salt compound with the structure shown in (I). The fluorescent probe can stain mitochondria in normal living cells, especially when the mitochondrial membrane potential decreases or disappears, it can still be fixed on mitochondria, indicating that the probe can track the dynamic changes of mitochondria. The probe also has good two-photon properties and can be used for deep tissue imaging. The probe has low toxicity and enables real-time tracking of the dynamic process of mitophagy. It is predicted that the probe of the present invention has broad application prospects in the field of fluorescent biomarkers. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110776458-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111362927-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110776458-A |
priorityDate |
2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |