http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109288895-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-02 |
filingDate | 2018-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109288895-B |
titleOfInvention | Preparation method of pharmaceutical composition |
abstract | The invention discloses a preparation method of a pharmaceutical composition, which comprises the following steps: extracting the cedrela sinensis in ethanol under the assistance of ultrasonic waves to obtain a cedrela sinensis extraction mixed solution; volatilizing the Chinese toon extraction mixed liquor until no ethanol smell exists, centrifuging, and taking precipitate to obtain a crude Chinese toon extract product; preparing the crude product of the Chinese toon extract into a diluent of the crude extract of the Chinese toon by using water; passing the diluted solution of the crude extract of Toona sinensis through a macroporous resin column; washing the macroporous resin column with distilled water until the effluent liquid is colorless; eluting the macroporous resin column with ethanol until the effluent liquid is colorless, and collecting the eluate; volatilizing and concentrating the eluent until no alcohol smell exists to obtain a pure Chinese toon extract product; freeze-drying the pure Chinese toon extract product to obtain pure Chinese toon extract product powder; mixing the Toona sinensis extract with curcumin to obtain the pharmaceutical composition. The pharmaceutical composition prepared by the method can effectively reduce the damage of cisplatin to organisms, increase the content of glutathione in vivo and reduce the content of malondialdehyde in vivo. |
priorityDate | 2018-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.