http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109280030-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 |
filingDate | 2017-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109280030-B |
titleOfInvention | Benzoazepine alkylarylpiperazine derivatives and their application in the preparation of medicines |
abstract | The invention discloses a benzazepine alkylarylpiperazine derivative and its application in preparing a medicine. The benzazepinealkylarylpiperazine derivative exhibits effects on the central nervous system, In particular, it has dual high-affinity activity on 5-HT 1A receptor and Sigma-1 receptor, exerts a variety of physiological and pharmacological effects in the body, and can be used as a pharmaceutical active substance, especially for antidepressant, anxiolytic, antidepressant Bipolar disorder, anti-neuropathic pain, and can also be used as an intermediate in the preparation of other pharmaceutically active compounds. The compound of the present invention has remarkable medicinal effect, small toxic and side effects, can meet the needs of clinical application, and is a compound with the following structural formula (IV) or its free base or salt: |
priorityDate | 2017-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 194.