http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109265554-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-40 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-26 |
| filingDate | 2018-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109265554-B |
| titleOfInvention | Angiotensin II immunogen and preparation method thereof |
| abstract | The invention provides an angiotensin II immunogen and a preparation method thereof, when the N-terminal of angiotensin II is connected to a carrier protein, a derivative of angiotensin II is firstly synthesized, the derivative of angiotensin II is that a section of polypeptide is added at the N-terminal of angiotensin II to be used as a connecting arm, the connecting arm comprises a flexible peptide, the flexible peptide consists of Gly and Ser amino acid residues, wherein the Gly is distributed at two sides of Ser, and the twisting of the connecting arm is facilitated; the angiotensin II derivative can effectively reduce the steric hindrance effect of the carrier protein on angiotensin II small molecule hapten, and-OH on a Ser side chain can increase the water solubility of angiotensin II molecules to a certain extent; the angiotensin II immunogen prepared by the invention has the advantages of simple preparation method, low cost, strong immunogenicity and the like, and is suitable for preparing angiotensin II antibodies. |
| priorityDate | 2018-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.