http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109265474-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-104 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2001-302 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B57-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 |
| filingDate | 2018-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109265474-B |
| titleOfInvention | Compound, aggregation-induced emission probe, and preparation method and application thereof |
| abstract | The invention belongs to the technical field of biological imaging, and discloses a compound, an aggregation-induced emission probe, and a preparation method and application thereof. The compound is a compound of formula III or IV. The aggregation-inducing luminescent probe comprises at least one compound of formula III or IV. The invention also discloses a preparation method of the compounds shown in the formulas III and IV. The compound can effectively overcome the defect of aggregation-induced quenching of the traditional fluorescent dye, realizes specificity and high signal-to-noise ratio fluorescence imaging of the A beta plaque, has the advantages of high luminous efficiency, large Stokes shift and the like, can be used as an aggregation-induced luminescent probe, and has a neuroprotective effect. In addition, the invention also discloses application of the compound in an A beta plaque specific fluorescence imaging agent and nerve cell protection, and monitoring A beta fiber formation or depolymerization A beta fiber. |
| priorityDate | 2018-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.