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filingDate 2018-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109265339-B
titleOfInvention Polygonum capitatum active component, extraction method and application
abstract The invention belongs to the technical field of traditional Chinese medicine extraction, and particularly relates to an active component of polygonum capitatum, an extraction method and application, wherein the extracted active component comprises gallic acid, quercetin and quercetin, and the extraction process comprises the following steps: mixing polygonum capitatum with ethanol according to a material-liquid ratio of 1:25g/mL, performing reflux extraction at 80 ℃ for 1.5 hours to obtain a first extracting solution and filter residue, performing reflux extraction on the filter residue under the same conditions for one time, combining the two extracting solutions, performing suction filtration, and performing reduced pressure concentration to obtain a polygonum capitatum ethanol extract; dissolving in water, sequentially extracting with petroleum ether, chloroform, ethyl acetate and n-butanol, and concentrating under reduced pressure to obtain ethyl acetate phase extract and n-butanol phase extract; separating by chromatography to obtain gallic acid, quercetin and quercetin. The gallic acid, the quercetin and the quercetin separated by the method can be applied to research on bacterial infection and treatment of diabetes.
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