| abstract |
The invention discloses a multifunctional dura mater repair material based on bionic design and a preparation method thereof, wherein the dura mater repair material comprises the following components: a hydrophobic and leak-proof polylactic acid layer, a hydrophilic and repairing hydrogel layer and an antibacterial, connecting and anti-adhesion chitosan-polylactic acid layer. The gelatin-SIS powder hydrogel is prepared on a double-layer electrostatic spinning film through electrostatic spinning polylactic acid films and electrostatic spinning chitosan-polylactic acid films. The dura mater repair material has low cost, and can simultaneously realize the effects of liquid leakage prevention, induced regeneration, adhesion prevention, immunity resistance and bacteria resistance. |