http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109260155-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
filingDate | 2018-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109260155-B |
titleOfInvention | Irinotecan liposome preparation and application thereof |
abstract | The invention relates to an irinotecan liposome preparation. The irinotecan liposome preparation provided by the invention takes monovalent sulfonate and disulfonate as internal aqueous phases, and stably encapsulates irinotecan in the form of insoluble sulfonate and disulfonate in the aqueous phase in the liposome, and obtains good slow release effect. The irinotecan liposome preparation provided by the invention has the advantages of high drug loading, easiness in preparation, good biocompatibility, capability of targeted modification and contribution to improvement of drug effect. The irinotecan liposome has long in-vivo half-life and high bioavailability. |
priorityDate | 2018-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 104.