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filingDate 2018-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109251877-B
titleOfInvention Bacillus natto Bn-SJLH001 with fat reducing function and application thereof
abstract The invention relates to a self-screened bacillus natto with the function of reducing fat accumulation (bacillus natto) Bacillus natto SJLH001, Bn-SJLH001 for short) and application thereof in probiotic foods. The strain has good in vitro probiotic activity such as in vitro fibrin decomposition, anticoagulation, antioxidation and the like, and has the functions of obviously losing weight, reducing the serum triglyceride level of a high-fat diet mouse, reducing the weight of white fat (epididymis fat, perirenal fat and mesenteric fat) at three different parts and reducing the diameter of fat cells. Meanwhile, the bacillus natto Bn-SJLH001 can regulate the number of intestinal dominant bacteria, change the expression of intestinal nutrient substances, metal ions and metabolite transport related genes, reduce the expression of a lipogenic factor gene (GSK-3 alpha/beta) and reduce the accumulation of uric acid in perirenal adipose tissues. In addition, based on the active functions of bacillus natto Bn-SJLH001 such as obvious fat reduction and the like, the invention also utilizes the bacillus natto Bn-SJLH001 to develop various forms of probiotic foods, such as probiotic tabletting candies and probiotic solid beverages.
priorityDate 2018-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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