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filingDate 2018-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_408a14a8c2af1d20193b411624e8bf7c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a088ce11621bf642843c9382b6d251f
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publicationDate 2019-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109248154-A
titleOfInvention A kind of rosuvastatin calcium tablet and preparation method thereof
abstract The invention provides a rosuvastatin calcium tablet and a preparation method thereof, which are mainly prepared from the following raw materials: in parts by mass, 1-10 parts of rosuvastatin calcium, 20-50 parts of a diluent, and a diluent disintegrant. 20-60 parts, disintegrant 5-40 parts and lubricant 0.2-1 part. The preparation method includes: (A) mixing rosuvastatin calcium, a diluent, a certain amount of diluting disintegrating agent and the disintegrating agent uniformly, and then adding an aqueous binder solution for granulation; (B) adding lubricant, The remaining amount of the diluted disintegrant is premixed with the disintegrant, tableted, and coated. The rosuvastatin calcium tablet of the present invention is prepared by adopting a wet process, and the dry granulation method used in the past is abandoned. The process requires low equipment and raw materials, and is easy to obtain and operate. The prepared tablet has stable drug effect, high safety and high dissolution rate.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113143882-A
priorityDate 2018-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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