http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109232885-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G73-028 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G73-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
| filingDate | 2018-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109232885-B |
| titleOfInvention | Modified dendritic PAMAM polymer and preparation method and application thereof |
| abstract | The invention belongs to the technical field of medical materials, and discloses a modified dendritic PAMAM polymer and a preparation method and application thereof. The structural formula of the modified dendritic PAMAM polymer is PAMAM- (NH-C (O) -O-R) n Wherein R is alkyl substituted by tertiary amine group, and-NH-in the structure is amino-NH from the tail end of PAMAM polymer 2 N is an integer greater than 0; the PAMAM polymer is preferably a generation 4 or generation 5 PAMAM polymer. The modified dendritic PAMAM polymer provided by the invention has the performances of temperature response, pH response and carbon dioxide response, and compared with unmodified PAMAM, the toxicity of the modified dendritic PAMAM polymer is obviously reduced. The modified dendritic PAMAM polymer is applied to a drug carrier. |
| priorityDate | 2018-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.