http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109232744-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43504 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64 |
filingDate | 2018-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109232744-B |
titleOfInvention | Improved ziconotide |
abstract | The invention relates to an improved ziconotide. The C end of the ziconotide is connected with the N end of the cell membrane penetrating peptide through two glycines, so that the obtained fusion peptide overcomes the defects that the ziconotide cannot pass through a blood brain barrier and cannot be injected intramuscularly, the surgical risk is high, the infection risk is high and the like. The improved ziconotide is suitable for intravenous, intraperitoneal or nasal administration, is convenient to operate, has small clinical risk, is applied through veins, abdominal cavities or nasal cavities, has long in-vivo drug effect action time, excellent in analgesic effect and small in side effect, and is suitable for large-scale clinical application. The improved ziconotide is simple to prepare, controllable in quality in a preparation process and a preparation process, and suitable for large-scale industrial production. |
priorityDate | 2018-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.