http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109232721-B

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24222
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filingDate 2018-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109232721-B
titleOfInvention Peptide segment 418-429 of highly conserved region of HCV envelope protein and application thereof
abstract The invention belongs to the technical field of biomedical engineering, and particularly relates to a peptide 418-429 of a highly conserved region of HCV envelope protein and application thereof. The peptide segment of the highly conserved region of the HCV envelope proteins provided by the invention is the peptide segment 418-429 of the highly conserved region of 1 HCV envelope proteins, which is provided by comparing the highly conserved region of the HCV envelope proteins through a sequence and combining the spatial structure of the envelope proteins, and the amino acid sequence is Gly-Ser-Trp-His-Ile-Asn-Ser-Thr-Ala-Leu-Asn-Cys, and animal experiments prove that the peptide segment can induce a high-efficiency antibody with broad-spectrum neutralization effect on 1-6 genotype HCV in vivo. The highly conserved peptide segment 418-429 derived from the HCV envelope protein can also be used for preparing vaccines for preventing and treating hepatitis C, and has the advantages of high conservation, wide application range and the like.
priorityDate 2018-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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