| abstract |
The present invention provides a kind of preparation method of benzofuran compounds in Herba Serissae, using the root of plant Herba Serissae as raw material, extracted after water/alcohol solvent system extracts, then through organic solvent, through further chromatography, can be enriched with to obtain benzofuran compounds active component and each monomeric compound.By the active component/monomeric compound by medically acceptable addition pharmaceutic adjuvant, solid pharmaceutical preparation and liquid preparation is made.Such compound is found through pharmacology activity research, it can promote transhipment of people's muscle cell C2C12 to glucose, and the NO that can obviously inhibit LPS to induce on RAW264.7 cell model is generated, show that such compound is developed with good application prospect in anti-diabetic and anti-inflammatory drug, it can be in the application in preparation treatment diabetes and various anti-inflammatory drugs. |