http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109232451-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d40285e27f4ed83b8728b0d477404958 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-12 |
| filingDate | 2018-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6016d2100c738487e0d5295ec2be413f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a29961acef66cd2097dfc3074d422e81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6aa82b2d0fdefef6b0f4a25c15b3a001 |
| publicationDate | 2019-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109232451-A |
| titleOfInvention | A kind of method for preparing thiazole |
| abstract | The invention discloses a method for preparing phenylephrine, which comprises the following steps: mixing mes-trimethylaniline and an inorganic acid aqueous solution to prepare an ammonium salt solution; mixing 3-mercapto-1, 2, 4-triazole, inorganic acid Alkali and alkanol are mixed to form triazole solution; ammonium salt solution, nitrite solution and inert solvent are mixed and then enter the first tubular reactor for diazotization reaction, and the material after diazotization reaction is mixed with triazole The solution and the reaction assistant are mixed, and the mixed solution enters the second tubular reactor for denitrification reaction. The material after denitrification reaction is allowed to stand for stratification. After adding acid to the water layer to adjust the pH, the solid crude product is obtained by centrifugation. Dry to obtain a white or pale yellow solid, that is, the thiazole is obtained. The invention adopts the continuous operation mode of tubular reaction, which is easier to realize process automation and improve production efficiency. Introducing an inert solvent into the diazotization and denitrogenation reactions can in-situ extract tar and other colored impurities and improve the purity of the product. |
| priorityDate | 2018-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.