http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109232446-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1059 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1044 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
| filingDate | 2018-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109232446-B |
| titleOfInvention | Preparation method of quinoxaline fluorescent probe and application of quinoxaline fluorescent probe in detection of G-quadruplex |
| abstract | The invention provides a preparation method of a quinoxaline fluorescent probe and application thereof in detecting a G-quadruplex, wherein the structural formula of the quinoxaline fluorescent probe is as follows: wherein R1 adopts at least one of N-methylpiperazine, morpholinyl and diethylamino, R2 adopts F and methyl, and R3 adopts at least one of F, methyl, N-methylpiperazine and triazolyl. Compared with the prior art, the invention has the following advantages: (1) the probe is simple to prepare, easy to obtain, stable in structure and convenient to store. (2) The probe provided by the invention can specifically detect the G-quadruplex structure, realizes the distinction of the G-quadruplex structure from other secondary structures, can identify the secondary structure of a nucleic acid sample by using a simple fluorescence spectrometer even without any instrument through visual observation, is quick, simple and convenient to operate and low in cost, and can realize field detection. (3) The probe has no obvious influence on the secondary structure of the nucleic acid to be detected, and can accurately detect the original structure of the nucleic acid. |
| priorityDate | 2018-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.