http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109232365-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c34545d5608f375cb166f78353663169 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-38 |
| filingDate | 2018-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_046912eeb0dfe1a63da6a1ccad63f2ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78be191af9e2f96bdc060c90dda11cb0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74884a6072e0b9414a0e4f60137d174a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a35254f037e3f8083a1259e0297f135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c2d6c73d8a42983b61c78128dd623d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcf8556cbfb04666aea2fdda1e6c131b |
| publicationDate | 2019-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109232365-A |
| titleOfInvention | A kind of preparation method of 3- allyl -3-hydroxyindole ketone and its derivative |
| abstract | The invention discloses a kind of method for preparing 3- allyl -3-hydroxyindole ketone and its derivative, the reactant used includes R 1 Substituted 3-hydroxyindole ketone (1) and allyl substrate (2), catalyst are [Ir (cod) Cl] 2 , synthetic route is as follows: Wherein, R 1 Select H, methyl, methoxyl group, any one or any several composition in F, Cl and Br substituent group；R 1 Substituted position is any one in 4- to 7- or several positions on phenyl ring；PG selects H, methyl, benzyl substituent, substituted benzyl substituent group, any one or any several composition in menaphthyl substituent group；R 2 Select any one in phenyl, substituted-phenyl, naphthalene, substituted naphthyl, piperonyl cyclonene, pyridine, alkyl or substitution alkyl；LG selects OAc, OCO 2 Any one in Me, OBoc, Br substituent group.3- allyl -3-hydroxyindole ketone prepared by the present invention with continuous chiral centre, enantioselectivity highest > 99%, cis-selectivity are up to 11:1, and mild condition, high income. |
| priorityDate | 2018-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.