http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109232357-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-38 |
| filingDate | 2018-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109232357-B |
| titleOfInvention | Method for catalytically synthesizing 3-pyrroline-2-ketone in emulsion by titanocene dichloride in cooperation with Bronsted acid |
| abstract | The invention discloses a method for catalytically synthesizing 3-pyrroline-2-ketone in emulsion by titanocene dichloride in cooperation with Bronsted acid, wherein titanocene dichloride and Bronsted acid are adopted in the method Acid is used as a catalyst, substituted benzene and water are used as solvents, an emulsion system is constructed, and the aniline compound and ethyl pyruvate or methyl pyruvate are subjected to intermolecular dehydration under mild conditions and undergo a ring closing process to generate the 3-pyrroline-2-ketone compound. The method has the advantages of simple operation, mild reaction conditions, high selectivity, effective avoidance of generation of by-products of quinoline and polysubstituted hydrogenated quinoline, less catalyst consumption, lower cost, good substrate applicability and high yield of the target compound, and can be widely used for preparing a natural product, namely the pyrrolinone compound. |
| priorityDate | 2018-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 86.