http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109232317-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-584 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-30 |
| filingDate | 2018-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109232317-B |
| titleOfInvention | Preparation method of ultraviolet absorbent etoriciline |
| abstract | The invention relates to a preparation method of an ultraviolet absorbent etoricine. The preparation method comprises the following steps: (1) adding benzophenone, ethyl cyanoacetate and a catalyst into a reaction vessel, and reacting for 12-24h at 60-120 ℃ under a vacuum condition; the catalyst is a combination of two or more than two amino acids, wherein at least one acidic amino acid and one neutral amino acid are contained, and the molar ratio of the acidic amino acid to the neutral amino acid is 1:10 to 10: 1; (2) adding water washing reaction solution, distilling the obtained water layer at 40-100 deg.C under reduced pressure, concentrating, cooling, filtering, and recovering filter cake; the obtained organic layer is decompressed and distilled to recover the raw materials which are not completely reacted; (3) and (3) adding ethanol into the distillation residues of the organic layer in the step (2) for recrystallization, and carrying out solid-liquid separation to obtain the product. The invention uses the amino acid catalyst to replace the catalyst in the prior preparation process, uses hot water for washing and separating, recycles the catalyst after water evaporation under reduced pressure, and has low production cost, short reaction time, good product quality and high yield. |
| priorityDate | 2018-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.