abstract |
The present invention provides pharmaceutical compositions comprising human immature dental pulp stem cells (hIDPSCs), wherein the hIDPSCs express CD44 and CD13. The present invention also provides methods of treating a neurological disease or disorder comprising systemically administering to a subject a pharmaceutical composition comprising hIDPSCs, wherein the hIDPSCs express CD44 and CD13. For example, for the treatment of neurological diseases or disorders, including supporting neuroprotective mechanisms in subjects diagnosed with early stage HD or repairing lost DA neurons in subjects diagnosed with PD. |