http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109207423-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-1369 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-15 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0655 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 |
filingDate | 2018-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109207423-B |
titleOfInvention | Novel induction system and induction method for promoting mesenchymal stem cells to become chondrogenic differentiation |
abstract | The invention discloses a novel induction system and an induction method for promoting mesenchymal stem cells to be chondrogenic differentiated. The invention optimizes the chondrogenic induction system of the mesenchymal stem cells, innovatively combines KGN pretreatment with the traditional induction factor TGF-beta 3 to form a new chondrogenic differentiation induction system: in the in vitro culture process of the seed cells, the mesenchymal stem cells can be efficiently differentiated to the chondrocytes by KGN pretreatment and TGF-beta 3 induction, and the formed chondrocytes have stable phenotype and no obvious ossification tendency. The invention obviously improves the chondrogenic differentiation efficiency of the mesenchymal stem cells and can better play the role of the mesenchymal stem cells as cartilage tissue engineering seed cells. |
priorityDate | 2018-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.