http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109206471-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-0031 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00 |
| filingDate | 2017-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109206471-B |
| titleOfInvention | A kind of preparation method of Hasinide |
| abstract | The present invention provides a preparation method of hacinide, comprising: 1) chlorination reaction: in the presence of SO 2 , compound 1 reacts with a chlorination reagent to generate compound 2, and the chlorination reagent is selected from acetyl chloride, propionyl chloride, One or more of benzoyl chloride, lithium chloride, carbon tetrachloride, chlorosuccinimide, and dichlorohydantoin; 2) ring-opening reaction: compound 2 reacts with hydrogen fluoride to obtain hacinide. The beneficial effects of the invention are that the reaction conditions are mild, the environment is friendly, the operation is easy, the cost is low, and it has industrial value, can effectively control side reactions, and improve the reaction yield and quality; no high-risk reactions are involved in the process design, and it is easy to realize industrialization; There is a high pollution reaction, which reduces the pressure of environmental protection treatment. |
| priorityDate | 2017-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.