http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109182564-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-689 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-689 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-04 |
filingDate | 2018-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109182564-B |
titleOfInvention | Method for detecting and analyzing toxicity and pathogenicity of helicobacter pylori |
abstract | The invention discloses a method for detecting and analyzing toxicity and pathogenicity of helicobacter pylori, which comprises the following steps: carrying out DNA extraction and whole genome sequence detection on a helicobacter pylori target strain, and carrying out whole genome sequencing data analysis and pathogenic related gene specificity analysis according to the whole genome sequence detection result; 1) typing and classifying the pathogenic related genes; 2) counting the reads number of pathogenic related genes according to the detection result of the whole genome sequence; 3) respectively statistically comparing the important parting genes to the percentage of respective reference sequences; 4) carrying out typing judgment on the important typing genes and carrying out functional integrity judgment on other pathogenic related genes; 5) according to the judgment result, important typing genes and other pathogenic related genes are judged to have toxicity, functional integrity and functional significance interpretation. The invention has great significance for deeply understanding the pathogenic mechanism of Hp and guiding the personalized treatment of Hp infected patients, and clinical research and teaching. |
priorityDate | 2018-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 311.