http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109182451-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-26 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26 |
filingDate | 2018-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109182451-B |
titleOfInvention | Novel specific probe reaction of cytochrome CYP3A7 enzyme and application thereof |
abstract | The invention provides a novel specific probe reaction of cytochrome CYP3A7 enzyme and application thereof: the 19-hydroxylation reaction of deoxycholyl glycine and the 19-hydroxylation reaction of deoxycholyl taurine are used as probe reactions of CYP3A7 enzyme to detect the activity of the enzyme; the method takes deoxycholic glycine or deoxycholic taurine as a probe substrate, and can realize the quantitative detection of the CYP3A7 enzyme activity in biological samples from different sources by quantitatively measuring the generation rate of a specific reaction product, namely 19-hydroxydeoxycholic glycine or 19-hydroxydeoxycholic taurine, in unit time as an evaluation index of the cytochrome CYP3A7 enzyme activity. |
priorityDate | 2018-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 364.