http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109182435-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
filingDate | 2018-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109182435-B |
titleOfInvention | Preparation method of biological source dipeptidyl peptidase-IV inhibitor |
abstract | The invention relates to the technical field of protein extraction, and provides a preparation method of a biological source dipeptidyl peptidase-IV inhibitor in order to solve the problems of a large amount of byproducts generated in the processing process of Nibea japonica and low resource utilization rate, which comprises the following steps: (1) pretreating the skin of the Nibea japonica to obtain skin powder, extracting collagen from the skin powder, and centrifugally drying to obtain the collagen of the skin of the Nibea japonica; (2) carrying out enzymolysis on the skin collagen of the Nibea japonica obtained in the step (1) by using a complex enzyme to obtain the skin collagen peptide of the Nibea japonica; (3) screening the collagen peptide of the fish skin of the Nibea japonica through a dipeptidyl peptidase screening kit to obtain the biogenic dipeptidyl peptidase-IV inhibitor. The invention takes the skin of the Nibea japonica as the main raw material, prepares the dipeptidyl peptidase-IV inhibiting peptide by a relatively high-efficiency process, and the inhibiting peptide has good effect of inhibiting dipeptidyl peptidase-4 and good effect of resisting hyperglycemia. |
priorityDate | 2018-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 105.