http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109180652-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
| filingDate | 2018-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109180652-B |
| titleOfInvention | Preparation process of benzopyran nitrile fluorescent probe molecule for detecting Cys |
| abstract | The invention discloses a preparation process of benzopyran nitrile fluorescent probe molecules for selectively detecting Cys, which is characterized by comprising the following steps: compound I (48 mg,0.14 mmol) was accurately weighed under nitrogen and dissolved in dehydrated dichloromethane (10 mL), and methyl trifluoromethanesulfonate (92 mg,0.56 mmol) was added to the mixed solution and stirred at room temperature for not less than 12 hours. And (3) filtering the precipitate after the reaction is finished, washing the precipitate by using absolute ethyl alcohol and ether to obtain a crude product red powder, and separating and purifying by column chromatography, wherein an eluent: dichloromethane/methanol =20/1 to yield DCM-q as an orange-red powder (36 mg, 50%). The product DCM-q is easy to obtain, and the probe molecule is mainly used for selectively detecting cysteine (Cys) in biological thiol. |
| priorityDate | 2018-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 388.