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filingDate 2018-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109180478-B
titleOfInvention Diphenheptane compounds, preparation method and application thereof
abstract The invention relates to the technical field of compound synthesis, in particular to a diphenylheptane compound and application thereof, wherein the structural formula of the compound is as follows: wherein R is 1 、R 2 Are all cyclopropane formyl; or R 1 Is H, R 2 Is cyclopropanecarbonyl; or R 1 Is H, R 2 Is m-chlorobenzoyl; or R 1 Is H, R 2 Is composed of Or R1 and R2 are both Or R 1 Is H, R 2 Is composed of R 3 F, Br, trifluoromethyl or tert-butyl; or R 1 、R 2 Are all made of R 3 Is an acetamido group. The compound of the invention has psoriasis bioactivity and has therapeutic effect on some immunosuppressive diseases. The compound of the invention is prepared into various pharmaceutically acceptable forms, such as tablets, pills, capsules, injections, suspending agents or emulsions, and hopefully replaces part of the existing psoriasis treatment medicines in the future.
priorityDate 2018-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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