http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109142506-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-64 |
| filingDate | 2017-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109142506-B |
| titleOfInvention | Method for relatively quantifying N-sugar chain based on mass spectrum |
| abstract | The invention belongs to the technical field of biochemical analysis, and relates to a mass spectrum-based method for relatively quantifying N-sugar chains 3+ /Lu 3+ Both the two-step reaction has higher derivatization efficiency; the test result shows that the ionization efficiency of the sugar chain in a MALDI-MS negative ion reflection mode can be improved and the fragmentation of the sugar chain in a mass spectrum can be improved after the derivative of the DOTA chelated with the rare earth metal ions, so that the sugar chain structure analysis is facilitated. The method is used for displaying the result of the differential analysis of the expression level of the N-sugar chain in the serum of the colorectal cancer patient and the normal human serum, can realize multi-label marking quantification by chelating different rare earth metal ions, and has good quantification accuracy and repeatability. |
| priorityDate | 2017-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.