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filingDate 2018-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_986ca1472a30657f3360cd24a0ed1a78
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publicationDate 2019-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109142486-A
titleOfInvention A kind of preparation method of the Photoelectrochemistrbiosensor biosensor for microRNA detection
abstract The invention discloses a kind of for detecting the preparation method of the annular metal iridium complex biosensor of microRNA.Design, which has synthesized one kind, first can be intercalated in the annular metal iridium complex of DNA double chain as photoelectric material.Capture hair clip DNA is fixed on to the working electrode that this sensor is made in the ITO electrode modified.In the presence of target microRNA, its neck portion is discharged with capture hair clip DNA hybridization fixed on working electrode, the hair clip neck portion of release then hybridizes chain reaction with other two hair DNA phase mutual cross initiation, length dna double-chain polymer is formed in working electrode surface, the polymer can be embedded in a large amount of annular metal iridium complexes to make signal amplify, and realize the highly sensitive detection to microRNA.The present invention has many advantages, such as that high sensitivity, specificity is good, stability is good.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113201580-A
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priorityDate 2018-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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