| abstract |
Phthalazinone compound, its preparation method, pharmaceutical composition and use, the structure of the phthalazinone compound is shown in formula I, the compound of formula I targets the virus nucleocapsid, and can be through the virus nucleocapsid. The interference of the body inhibits the replication of the virus, has the activity of effectively inhibiting the replication of the HBV DNA, and has good liver targeting, and can stably exist and accumulate in the liver. It is a new and effective anti-HBV Hepatitis virus inhibitor. |