http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109134381-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C03C23-0095 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C03C23-00 |
filingDate | 2018-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109134381-B |
titleOfInvention | Microfluidic synthesis18Method of F-FMISO |
abstract | The invention discloses a microfluidic synthesis 18 The method of F-FMISO relates to the fast and efficient preparation of Positron Emission Tomography (PET) imaging agent. The invention is characterized in that the inner wall of the microtube is modified and the microtube is quickly dried 18 F ion reagent, and is completed in microtube 18 F substitution labeling and hydrolysis reaction. By modifying the inner wall of the microtube to increase the adsorption area, the solution is injected into the microtube 18 F reagent solution is spread on the pipe wall to form a liquid film under the push of air flow, so that the evaporation area is increased, and meanwhile, hot air flow can conveniently pass through the hollow pipeline, thereby realizing quick drying, and the adsorption effect of the pipe wall can prevent the dried liquid film 18 F reagent is agglomerated and blown off, which is beneficial to fully mixing with the reaction reagent and is sequentially finished in the same microtube 18 F replaces the marking and hydrolyzes the two-step synthesis reaction, shortens the total synthesis operation time, and improves 18 F-FMISO synthesis yield. |
priorityDate | 2018-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.