http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109125737-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B22F9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6939 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B22F1-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B22F9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B22F1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
| filingDate | 2018-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109125737-B |
| titleOfInvention | Prodrug-loaded mesoporous nano ruthenium system, preparation method thereof and application of prodrug-loaded mesoporous nano ruthenium system in preparation of drug for treating drug-resistant bacterial infection |
| abstract | The invention belongs to the technical field of antibacterial drugs, and discloses a loaded prodrug and MoS 2 The mesoporous nano ruthenium system, the preparation method and the application in preparing the drug for treating drug-resistant bacterial infection. The preparation method comprises the following steps: (1) adding ruthenium trichloride and sodium borohydride into a hexadecyl trimethyl ammonium bromide solution to prepare mesoporous nano ruthenium; loading prodrug ascorbic acid, and encapsulating with hyaluronic acid to obtain encapsulated mesoporous nano ruthenium; (2) mixing MoS 2 Pre-coating the nano particles with quinolone antibiotics; the mesoporous nano ruthenium is coated on the surface of the encapsulated mesoporous nano ruthenium to obtain a mesoporous nano system. The loaded prodrug and MoS prepared by the method of the invention 2 The mesoporous nano system can be applied to the preparation of drugs for treating drug-resistant bacterial infection. The mesoporous nano system disclosed by the invention not only realizes a quick and effective killing effect, but also effectively disperses a stubborn biological membrane, so that embedded bacteria are inactivated, and the mesoporous nano system has a huge application prospect in biomedicine and the like. |
| priorityDate | 2018-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.