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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
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filingDate 2018-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109125707-B
titleOfInvention GnRH analog sustained-release composition and preparation method thereof
abstract The invention discloses a GnRH analog sustained-release composition and a preparation method thereof, belonging to the technical field of medicine. It consists of GnRH analogs and chitosan molecules covalently linked to GnRH analogs. The synthesis process of the GnRH analog sustained-release composition of the present invention is simple, and large-scale production can be realized by using conventional synthesis conditions. And as an oral long-acting sustained-release preparation, it can not only overcome the problem that GnRH analogs are easily degraded in the gastrointestinal tract and cannot be administered orally, but also prolong the action time of GnRH analogs in the body, thereby overcoming the need for GnRH analogs. The problem of long-term frequent injection and administration has strong practicality.
priorityDate 2018-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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