| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1274
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06 |
| filingDate |
2018-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03bad7566e5a48efacdbed418171c923
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82e158dea843355397fed407997988ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f756d8041533c82fc4b41bf03b01fba |
| publicationDate |
2019-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-109125267-A |
| titleOfInvention |
Preparation method and in vitro release performance of a lyotropic liquid crystal carrier with protective effect on curcumin |
| abstract |
The invention provides a lyotropic liquid crystal carrier with protective effect on curcumin. The ternary phase diagram of lecithin/geraniol/water system was constructed at 37℃, and different drug-loaded liquid crystal samples were prepared by selecting sample points to encapsulate curcumin in the phase diagram. The light and thermal stability and in vitro release behavior of curcumin in different liquid crystal samples were investigated. The results show that the drug-loaded liquid crystal has a sustained release effect on curcumin, which can reach 65% of the cumulative release in 40h; the curcumin encapsulated in the liquid crystal carrier is observed to have better stability to light and heat within a period of time. The drug residual rate in most liquid crystal samples was above 50%. It indicated that the lyotropic liquid crystal slowed down the degradation of curcumin and played a protective effect on curcumin. |
| priorityDate |
2018-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |