http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109096334-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5333 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-53 |
| filingDate | 2018-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109096334-B |
| titleOfInvention | Preparation method of chiral aryl phosphine oxide compound and derivative thereof |
| abstract | The invention relates to a preparation method of a chiral aryl phosphine oxide compound and a derivative thereof. Taking a phosphino-oxy compound and an o-methylene benzoquinone compound as raw materials, and obtaining a chiral aryl phosphino-oxy compound through nucleophilic addition of the o-methylene benzoquinone compound and the phosphino-oxy compound under the catalysis of a chiral squaramide organic catalyst. The invention adopts a route of directly constructing C-P bonds in one step by catalysis of a chiral squaramide organic catalyst, has mild reaction conditions and simple operation, can quickly and simply synthesize a series of chiral aryl phosphine oxide compounds, provides diversified compound frameworks, and has great significance for new drug screening and pharmaceutical technology. |
| priorityDate | 2018-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.